2021 Mercedes-Benz C-Class vs. Lexus IS

c-class vs lexus is

What’s the ultimate luxury sedan on the market today? If you’re shopping for a serious upgrade, then you’ve probably set your sights on the 2021 Mercedes-Benz C-Class vs. Lexus IS. While both brands have a reputation for excellence, the Mercedes-Benz C-Class has clear advantages in performance and interior comfort. Find out more with our 2021 Mercedes-Benz C-Class vs. Lexus IS comparison below:

2021 Mercedes-Benz C-Class


2021 Lexus IS

2.0L Inline-4 turbo

Base Engine

2.0L Inline-4 turbo
9G-TRONIC automatic


8-speed automatic
255 hp


241 hp
Rear-wheel drive


Rear-wheel drive
23 city/35 mpg MPG*

Fuel Economy

21 city/31 highway MPG
12.6 cubic feet

Trunk Volume

10.8 cubic feet

C-Class vs. IS: Performance Specs

Between the Mercedes-Benz and Lexus, both models have similar 2.0L turbocharged engines that deliver robust power on the Elizabethtown roads. However, the C-Class has the higher output between the two of them with 255 hp. The Lexus IS only reaches 241 hp by comparison. And while both models utilize standard rear-wheel drive, the Mercedes-Benz C-Class has a more refined 9G-TRONIC automatic transmission system. The Lexus IS is equipped with an eight-speed automatic transmission, which won’t feel quite as smooth overall.

C-Class vs. IS: Fuel Economy

While the two models may have similar powertrains and drivetrains, the Mercedes-Benz C-Class has a much higher EPA-estimated fuel economy compared to the Lexus IS. The C-Class generates 23 mpg in the city*, compared to the Lexus IS’s 21 mpg in the city. The difference is even greater on the Shelbyville highways with the C-Class generating 35 mpg* compared to just 31 mpg on the Lexus IS. That’s a difference of four miles per gallon, which can make a huge difference in annual fueling costs.

C-Class vs. IS: Dimensions

Finally, what about the interior dimensions? Both models have room for five passengers to stretch out and relax, the C-Class has extra cargo space that may come in handy during your Clarksville errands. Plus, the C-Class has extra room in the back for passengers to get comfortable. 

2021 Mercedes-Benz C-Class

  • Passenger Capacity: 5 passengers
  • Cargo Capacity: 12.6 cubic feet
  • Headroom: 37.1 inches (front), 37.1 inches (rear)
  • Legroom: 41.7 inches (front), 35.2 inches (rear)

2021 Lexus IS

  • Passenger Capacity: 5 passengers
  • Cargo Capacity: 10.8 cubic feet
  • Headroom: 38.2 inches (front), 36.9 inches (rear)
  • Legroom: 44.8 inches (front), 32.2 inches (rear)

Take Your Test Drive at Mercedes-Benz of Louisville

You’ve read all about the key differences between the 2021 Mercedes-Benz C-Class vs. Lexus IS, but why not experience our winner up close? Not only can you visit our dealership in Louisville, but you can also use our Online Shopper™ resource to buy from home – including delivery! Contact us with any questions.

*EPA estimated fuel economy. Compare the estimated mpg to the estimated mpg of other vehicles. You may get different mileage depending on how fast you drive, weather conditions and trip length. Your actual highway mileage will probably be less than the highway estimate.Back to content

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